Phenotype: 
Severe Early Childhood Obesity
Algorithm Type: 
Case, Control
Institution: 
Vanderbilt
Implementation Details: 

We performed manual review of 75 potential cases and 40 potential controls based on the ICD9 Exclusion Criteria (prior to review of BMI and height criteria).

a. Case Criteria: Manual review of 75 charts identified using the ICD9-based case exclusion criteria revealed that 74/75 were potential cases. PPV = 98.7

b. Control Criteria: Manual review of 40 charts identified using the ICD9-based control exclusion criteria revealed that 39/40 were potential controls. PPV = 97.5

The height and BMI percentile data for potential cases and controls were then evaluated for all potential cases and controls.  There are 4 severe early childhood obesity cases and 4 controls meeting the height and BMI criteria with GWAS data available from the Vanderbilt site.

True Positive: 
74.00
False Positive: 
1.00
True Positive: 
39.00
False Positive: 
1.00
Case Positive Predictive Value: 
0.99
Control Positive Predictive Value: 
0.98